Modalert 200mg is a prescription medication used to promote wakefulness in individuals experiencing excessive daytime sleepiness due to sleep disorders. It contains modafinil, a central nervous system stimulant-like agent that is commonly prescribed for narcolepsy, obstructive sleep apnea, and shift work sleep disorder.
? Product Name: Modalert 200mg
Generic Name: Modafinil
Manufacturer: Sun Pharmaceutical Industries
Form: Oral tablet
Strength: 200 mg
Class: Wakefulness-promoting agent / eugeroic
✅ Indications (Uses)
Modalert 100mg pill online is indicated for the treatment of:
Narcolepsy – sudden and uncontrollable episodes of deep sleep
Obstructive Sleep Apnea (OSA) – to reduce residual daytime sleepiness in patients using CPAP therapy
Shift Work Sleep Disorder (SWSD) – for individuals who experience sleepiness during scheduled waking hours due to night or rotating shift work
⚠️ Off-label use includes management of fatigue in multiple sclerosis, ADHD, and cognitive enhancement, though not officially approved for these indications.
⚙️ Mechanism of Action
While the exact mechanism is not fully understood, modafinil is thought to work by:
Inhibiting dopamine reuptake
Increasing activity in the hypothalamus
Modulating histamine, norepinephrine, and orexin systems
This results in increased wakefulness, enhanced attention, and reduced fatigue.
? Dosage & Administration
Standard adult dose: 200mg once daily
Narcolepsy/OSA: Taken in the morning
Shift Work Sleep Disorder: Taken approximately 1 hour before the start of the shift
Administration note: May be taken with or without food. Fatty meals may delay onset of action.
⏱️ Pharmacokinetics
Onset: 30–60 minutes
Half-life: Approximately 12–15 hours
Peak concentration: 2–4 hours post-dose
Metabolism: Primarily hepatic (CYP3A4)
⚠️ Side Effects
Common:
Headache
Nausea
Nervousness
Dizziness
Insomnia
Less common:
Elevated blood pressure
Anxiety
Back pain
Serious (rare):
Skin rash (Stevens-Johnson Syndrome)
Psychiatric symptoms (mania, aggression)
Allergic reactions
Discontinue immediately if signs of hypersensitivity or psychiatric symptoms occur.
? Drug Interactions
May reduce effectiveness of hormonal contraceptives
May alter metabolism of CYP3A4 substrates (e.g., certain statins, antifungals, antiretrovirals)
Potential additive effects with other stimulants
? Contraindications
Known hypersensitivity to modafinil or armodafinil
History of cardiac arrhythmias or severe hypertension (use with caution)
? Special Populations
Pregnancy: Not recommended; risk of congenital malformations
Lactation: Unknown if excreted in breast milk; avoid if possible
Pediatrics: Not approved for individuals under 18
Elderly: Use caution; monitor for cardiovascular effects
? Legal and Regulatory Status
United States: Schedule IV controlled substance
UK: Prescription-only medicine (POM)
India: Available by prescription (and commonly online)
Always ensure legal compliance when purchasing or importing Modalert.
? Patient Counseling Points
Do not exceed recommended dose
Avoid driving or operating machinery until the effect is known
Maintain adequate hydration
Do not substitute for adequate sleep
Inform your doctor about all medications and supplements
? Conclusion
Modalert 200mg is a clinically useful agent for improving wakefulness in people with sleep disorders. When used appropriately and under medical supervision, it can significantly improve quality of life. However, due to its stimulating properties and off-label use, careful evaluation of risks, side effects, and potential for misuse is essential.
