Wellness for Life Blog | Difference Between Adderall vs Vyvanse The side effects of Adderall vs Vyvanse can include increased heart rate, anxiety, and irritability. Both medicines may also affect focus differently depending on dosage and personal health. Knowing these differences helps reduce risks and make informed treatment decisions. At Wellness for Life Blog, we explain these effects clearly to help you avoid harmful mistakes. Visit our site now to get complete, easy-to-understand comparisons before making any decisions about your medication.